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Fc γ receptor IIIa/CD16a processing correlates with the expression of glycan-related genes in human natural killer cells
Many therapeutic monoclonal antibodies require binding to Fc γ receptors (FcγRs) for full effect and increasing the binding affinity increases efficacy. Preeminent among the five activating human FcγRs is FcγRIIIa/CD16a expressed by natural killer (NK) cells. CD16a is heavily processed, and recent r...
Guardat en:
| Publicat a: | J Biol Chem |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7948478/ https://ncbi.nlm.nih.gov/pubmed/33310702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015516 |
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