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Site-specific N-glycan Analysis of Antibody-binding Fc γ Receptors from Primary Human Monocytes
FcγRIIIa (CD16a) and FcγRIIa (CD32a) on monocytes are essential for proper effector functions including antibody dependent cellular cytotoxicity (ADCC) and phagocytosis (ADCP). Indeed, therapeutic monoclonal antibodies (mAbs) that bind FcγRs with greater affinity exhibit greater efficacy. Furthermor...
Gorde:
| Argitaratua izan da: | Mol Cell Proteomics |
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| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
The American Society for Biochemistry and Molecular Biology
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7000114/ https://ncbi.nlm.nih.gov/pubmed/31888963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA119.001733 |
| Etiketak: |
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