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Site-specific N-glycan Analysis of Antibody-binding Fc γ Receptors from Primary Human Monocytes
FcγRIIIa (CD16a) and FcγRIIa (CD32a) on monocytes are essential for proper effector functions including antibody dependent cellular cytotoxicity (ADCC) and phagocytosis (ADCP). Indeed, therapeutic monoclonal antibodies (mAbs) that bind FcγRs with greater affinity exhibit greater efficacy. Furthermor...
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| Publicat a: | Mol Cell Proteomics |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society for Biochemistry and Molecular Biology
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7000114/ https://ncbi.nlm.nih.gov/pubmed/31888963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA119.001733 |
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