ApoC-III is a novel inducer of calcification in human aortic valves

Calcific aortic valve disease (CAVD) occurs when subpopulations of valve cells undergo specific differentiation pathways, promoting tissue fibrosis and calcification. Lipoprotein particles carry oxidized lipids that promote valvular disease, but low-density lipoprotein–lowering therapies have failed...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Schlotter, Florian, de Freitas, Renata C.C., Rogers, Maximillian A., Blaser, Mark C., Wu, Pin-Jou, Higashi, Hideyuki, Halu, Arda, Iqbal, Farwah, Andraski, Allison B., Rodia, Cayla N., Kuraoka, Shiori, Wen, Jennifer R., Creager, Michael, Pham, Tan, Hutcheson, Joshua D., Body, Simon C., Kohan, Alison B., Sacks, Frank M., Aikawa, Masanori, Singh, Sasha A., Aikawa, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948477/
https://ncbi.nlm.nih.gov/pubmed/33334888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015700
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