ApoC-III is a novel inducer of calcification in human aortic valves

Calcific aortic valve disease (CAVD) occurs when subpopulations of valve cells undergo specific differentiation pathways, promoting tissue fibrosis and calcification. Lipoprotein particles carry oxidized lipids that promote valvular disease, but low-density lipoprotein–lowering therapies have failed...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Schlotter, Florian, de Freitas, Renata C.C., Rogers, Maximillian A., Blaser, Mark C., Wu, Pin-Jou, Higashi, Hideyuki, Halu, Arda, Iqbal, Farwah, Andraski, Allison B., Rodia, Cayla N., Kuraoka, Shiori, Wen, Jennifer R., Creager, Michael, Pham, Tan, Hutcheson, Joshua D., Body, Simon C., Kohan, Alison B., Sacks, Frank M., Aikawa, Masanori, Singh, Sasha A., Aikawa, Elena
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948477/
https://ncbi.nlm.nih.gov/pubmed/33334888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015700
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