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Elongin A regulates transcription in vivo through enhanced RNA polymerase processivity

Elongin is an RNA polymerase II (RNAPII)-associated factor that has been shown to stimulate transcriptional elongation in vitro. The Elongin complex is thought to be required for transcriptional induction in response to cellular stimuli and to ubiquitinate RNAPII in response to DNA damage. Yet, the...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Wang, Yating, Hou, Liming, Ardehali, M. Behfar, Kingston, Robert E., Dynlacht, Brian D.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948402/
https://ncbi.nlm.nih.gov/pubmed/33298525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015876
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