Proteomic and bioinformatic profiling of neutrophils in CLL reveals functional defects that predispose to bacterial infections

Patients with chronic lymphocytic leukemia (CLL) typically suffer from frequent and severe bacterial infections. Although it is well known that neutrophils are critical innate immune cells facilitating the early defense, the underlying phenotypical and functional changes in neutrophils during CLL re...

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Bibliografske podrobnosti
izdano v:Blood Adv
Main Authors: Subramaniam, Nirojah, Bottek, Jenny, Thiebes, Stephanie, Zec, Kristina, Kudla, Matthias, Soun, Camille, de Dios Panal, Elena, Lill, Julia K., Pfennig, Aaron, Herrmann, Ralf, Bruderek, Kirsten, Rahmann, Sven, Brandau, Sven, Johansson, Patricia, Reinhardt, Hans Christian, Dürig, Jan, Seiffert, Martina, Bracht, Thilo, Sitek, Barbara, Engel, Daniel Robert
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2021
Teme:
Phagocytes, Granulocytes, and Myelopoiesis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948268/
https://ncbi.nlm.nih.gov/pubmed/33651101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002949
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