Proteomic and bioinformatic profiling of neutrophils in CLL reveals functional defects that predispose to bacterial infections

Patients with chronic lymphocytic leukemia (CLL) typically suffer from frequent and severe bacterial infections. Although it is well known that neutrophils are critical innate immune cells facilitating the early defense, the underlying phenotypical and functional changes in neutrophils during CLL re...

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Enregistré dans:
Détails bibliographiques
Publié dans:Blood Adv
Auteurs principaux: Subramaniam, Nirojah, Bottek, Jenny, Thiebes, Stephanie, Zec, Kristina, Kudla, Matthias, Soun, Camille, de Dios Panal, Elena, Lill, Julia K., Pfennig, Aaron, Herrmann, Ralf, Bruderek, Kirsten, Rahmann, Sven, Brandau, Sven, Johansson, Patricia, Reinhardt, Hans Christian, Dürig, Jan, Seiffert, Martina, Bracht, Thilo, Sitek, Barbara, Engel, Daniel Robert
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2021
Sujets:
Phagocytes, Granulocytes, and Myelopoiesis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948268/
https://ncbi.nlm.nih.gov/pubmed/33651101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002949
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