Proteomic and bioinformatic profiling of neutrophils in CLL reveals functional defects that predispose to bacterial infections

Patients with chronic lymphocytic leukemia (CLL) typically suffer from frequent and severe bacterial infections. Although it is well known that neutrophils are critical innate immune cells facilitating the early defense, the underlying phenotypical and functional changes in neutrophils during CLL re...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Subramaniam, Nirojah, Bottek, Jenny, Thiebes, Stephanie, Zec, Kristina, Kudla, Matthias, Soun, Camille, de Dios Panal, Elena, Lill, Julia K., Pfennig, Aaron, Herrmann, Ralf, Bruderek, Kirsten, Rahmann, Sven, Brandau, Sven, Johansson, Patricia, Reinhardt, Hans Christian, Dürig, Jan, Seiffert, Martina, Bracht, Thilo, Sitek, Barbara, Engel, Daniel Robert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2021
Assuntos:
Phagocytes, Granulocytes, and Myelopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948268/
https://ncbi.nlm.nih.gov/pubmed/33651101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002949
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