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Dnmt3a-null hematopoietic progenitor stem cells expand after busulfan treatment

Mutations in the gene encoding DNA Methyltransferase 3A ( DNMT3A ) are the most common in c lonal hematopoiesis (CH), an age-related condition that was recently demonstrated to affect outcomes in patients undergoing hematopoietic stem cell transplant (HSCT). Recent studies showed patients with CH ha...

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Detalles Bibliográficos
Publicado en:Exp Hematol
Main Authors: Chen, Jichun, Matatall, Katie A., Feng, Xingmin, Hormaechea-Agulla, Daniel, Maharjan, Mukesh, Young, Neal, King, Katherine Y.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948254/
https://ncbi.nlm.nih.gov/pubmed/32961298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2020.09.192
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