Chemical Cocktail Induces Hematopoietic Reprogramming and Expands Hematopoietic Stem/Progenitor Cells

Generation of hematopoietic stem/progenitor cells (HSPCs) via cell expansion or cell reprogramming has been widely achieved by overexpression of transcription factors. Herein, it is reported that without introducing exogenous genes, mouse fibroblasts can be reprogrammed into hemogenic cells based on...

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Publicado en:Adv Sci (Weinh)
Autores principales: Zhou, Yi, Zhu, Xingli, Dai, Yuting, Xiong, Shumin, Wei, Chuijin, Yu, Pei, Tang, Yuewen, Wu, Liang, Li, Jianfeng, Liu, Dan, Wang, Yanlin, Chen, Zhu, Chen, Sai‐Juan, Huang, Jinyan, Cheng, Lin
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Full Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6947705/
https://ncbi.nlm.nih.gov/pubmed/31921559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201901785
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