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Hypomethylating Agents and Immunotherapy: Therapeutic Synergism in Acute Myeloid Leukemia and Myelodysplastic Syndromes

Decitabine and guadecitabine are hypomethylating agents (HMAs) that exert inhibitory effects against cancer cells. This includes stimulation of anti-tumor immunity in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) patients. Treatment of AML and MDS patients with the HMAs confers up...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Wong, Kah Keng, Hassan, Rosline, Yaacob, Nik Soriani
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7947882/
https://ncbi.nlm.nih.gov/pubmed/33718188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.624742
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