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Thyroid Hormone Induces DNA Demethylation in Xenopus Tadpole Brain

Thyroid hormone (T(3)) plays pivotal roles in vertebrate development, acting via nuclear T(3) receptors (TRs) that regulate gene transcription by promoting post-translational modifications to histones. Methylation of cytosine residues in deoxyribonucleic acid (DNA) also modulates gene transcription,...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Raj, Samhitha, Kyono, Yasuhiro, Sifuentes, Christopher J, Arellanes-Licea, Elvira del Carmen, Subramani, Arasakumar, Denver, Robert J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7947600/
https://ncbi.nlm.nih.gov/pubmed/32865566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqaa155
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