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Liganded Thyroid Hormone Receptors Transactivate the DNA Methyltransferase 3a Gene in Mouse Neuronal Cells

Thyroid hormone (T(3)) is essential for proper neurological development. The hormone, bound to its receptors, regulates gene transcription in part by modulating posttranslational modifications of histones. Methylation of DNA, which is established by the de novo DNA methyltransferase (DNMT)3a and DNM...

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Vydáno v:Endocrinology
Hlavní autoři: Kyono, Yasuhiro, Subramani, Arasakumar, Ramadoss, Preeti, Hollenberg, Anthony N., Bonett, Ronald M., Denver, Robert J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007891/
https://ncbi.nlm.nih.gov/pubmed/27387481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1529
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