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Developmental and Thyroid Hormone Regulation of the DNA Methyltransferase 3a Gene in Xenopus Tadpoles

Thyroid hormone is essential for normal development in vertebrates. In amphibians, T3 controls metamorphosis by inducing tissue-specific gene regulation programs. A hallmark of T3 action is the modification of chromatin structure, which underlies changes in gene transcription. We found that mRNA for...

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Publié dans:Endocrinology
Auteurs principaux: Kyono, Yasuhiro, Sachs, Laurent M., Bilesimo, Patrice, Wen, Luan, Denver, Robert J.
Format: Artigo
Langue:Inglês
Publié: Endocrine Society 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133355/
https://ncbi.nlm.nih.gov/pubmed/27779916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1465
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