Prognostic and predictive effect of KRAS gene copy number and mutation status in early stage non-small cell lung cancer patients

BACKGROUND: In the current analysis, we characterize the prognostic significance of KRAS mutations with concomitant copy number aberrations (CNA) in early stage non-small cell lung cancer (NSCLC), and evaluate the ability to predict survival benefit from adjuvant chemotherapy. METHODS: Clinical and...

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Veröffentlicht in:Transl Lung Cancer Res
Hauptverfasser: Fung, Andrea S., Karimi, Maryam, Michiels, Stefan, Seymour, Lesley, Brambilla, Elisabeth, Le-Chevalier, Thierry, Soria, Jean-Charles, Kratzke, Robert, Graziano, Stephen L., Devarakonda, Siddhartha, Govindan, Ramaswamy, Tsao, Ming-Sound, Shepherd, Frances A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: AME Publishing Company 2021
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7947394/
https://ncbi.nlm.nih.gov/pubmed/33718025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tlcr-20-927
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