Rat prostaglandin EP3 receptor is highly promiscuous and is the sole prostanoid receptor family member that regulates INS‐1 (832/3) cell glucose‐stimulated insulin secretion

Chronic elevations in fatty acid metabolites termed prostaglandins can be found in circulation and in pancreatic islets from mice or humans with diabetes and have been suggested as contributing to the β‐cell dysfunction of the disease. Two‐series prostaglandins bind to a family of G‐protein‐coupled...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Sandhu, Harpreet K., Neuman, Joshua C., Schaid, Michael D., Davis, Sarah E., Connors, Kelsey M., Challa, Romith, Guthery, Erin, Fenske, Rachel J., Patibandla, Chinmai, Breyer, Richard M., Kimple, Michelle E.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7947324/
https://ncbi.nlm.nih.gov/pubmed/33694300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.736
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