Minimally Invasive Nasal Depot (MIND) Technique for Direct BDNF AntagoNAT Delivery to the Brain

The limitations of central nervous system (CNS) drug delivery conferred by the blood-brain barrier (BBB) have been a significant obstacle in the development of large molecule therapeutics for CNS disease. Though significantly safer than direct CNS administration via intrathecal (IT) or intracerebrov...

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Библиографические подробности
Опубликовано в: :J Control Release
Главные авторы: Padmakumar, Smrithi, Jones, Gregory, Pawar, Grishma, Khorkova, Olga, Hsiao, Jane, Kim, Jonghan, Amiji, Mansoor M., Bleier, Benjamin S.
Формат: Artigo
Язык:Inglês
Опубликовано: 2021
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946770/
https://ncbi.nlm.nih.gov/pubmed/33484777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2021.01.027
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