Minimally Invasive Nasal Depot (MIND) Technique for Direct BDNF AntagoNAT Delivery to the Brain

The limitations of central nervous system (CNS) drug delivery conferred by the blood-brain barrier (BBB) have been a significant obstacle in the development of large molecule therapeutics for CNS disease. Though significantly safer than direct CNS administration via intrathecal (IT) or intracerebrov...

Full description

Saved in:
Bibliographic Details
Published in:J Control Release
Main Authors: Padmakumar, Smrithi, Jones, Gregory, Pawar, Grishma, Khorkova, Olga, Hsiao, Jane, Kim, Jonghan, Amiji, Mansoor M., Bleier, Benjamin S.
Format: Artigo
Language:Inglês
Published: 2021
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946770/
https://ncbi.nlm.nih.gov/pubmed/33484777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2021.01.027
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items