Accelerated clearance and degradation of cell free HIV by neutralizing antibodies occurs via FcγRIIb on liver sinusoidal endothelial cells by endocytosis

Neutralizing antibodies suppress HIV infection by accelerating viral clearance from blood circulation, in addition to neutralization. The elimination mechanism is largely unknown. We determined that human liver sinusoidal endothelial cells (LSEC) express FcγRIIb as the lone Fc gamma receptor, and, u...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:J Immunol
Main Authors: Turman, James M., Cheplowitz, Alana M., Tiwari, Charu, Thomas, Thushara, Joshi, Dhruvi, Bhat, Menakshi, Wu, Qian, Pong, Erik, Chu, Seung Y., Szymkowski, David E., Sharma, Amit, Seveau, Stephanie, Robinson, John M., Kwiek, Jesse J., Burton, Dennis, Rajaram, Murugesan VS., Kim, Jonghan, Hangartner, Lars, Ganesan, Latha P.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2021
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946731/
https://ncbi.nlm.nih.gov/pubmed/33568400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000772
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla