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cAbl kinase regulates inflammasome activation and pyroptosis via ASC phosphorylation
Inflammasome activation is regulated in part by the post-translational modification of inflammasome proteins. Tyrosine phosphorylation is one possible modification. Having previously shown that the protein tyrosine kinase (PTK) inhibitor AG126 greatly inhibits inflammasome activation, we sought to u...
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| Veröffentlicht in: | J Immunol |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7946721/ https://ncbi.nlm.nih.gov/pubmed/33568399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000969 |
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