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cAbl kinase regulates inflammasome activation and pyroptosis via ASC phosphorylation

Inflammasome activation is regulated in part by the post-translational modification of inflammasome proteins. Tyrosine phosphorylation is one possible modification. Having previously shown that the protein tyrosine kinase (PTK) inhibitor AG126 greatly inhibits inflammasome activation, we sought to u...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Gavrilin, Mikhail A., Prather, Evan R., Vompe, Alex D., McAndrew, Christian C., Wewers, Mark D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946721/
https://ncbi.nlm.nih.gov/pubmed/33568399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000969
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