Antagonistic roles for Ataxin-2 structured and disordered domains in RNP condensation

Ataxin-2 (Atx2) is a translational control molecule mutated in spinocerebellar ataxia type II and amyotrophic lateral sclerosis. While intrinsically disordered domains (IDRs) of Atx2 facilitate mRNP condensation into granules, how IDRs work with structured domains to enable positive and negative reg...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Singh, Amanjot, Hulsmeier, Joern, Kandi, Arvind Reddy, Pothapragada, Sai Shruti, Hillebrand, Jens, Petrauskas, Arnas, Agrawal, Khushboo, RT, Krishnan, Thiagarajan, Devasena, Jayaprakashappa, Deepa, VijayRaghavan, K, Ramaswami, Mani, Bakthavachalu, Baskar
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2021
Konular:
Cell Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946432/
https://ncbi.nlm.nih.gov/pubmed/33689682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.60326
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller