Epigenomic characterization of latent HIV infection identifies latency regulating transcription factors

Transcriptional silencing of HIV in CD4 T cells generates a reservoir of latently infected cells that can reseed infection after interruption of therapy. As such, these cells represent the principal barrier to curing HIV infection, but little is known about their characteristics. To further our unde...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Jefferys, Stuart R., Burgos, Samuel D., Peterson, Jackson J., Selitsky, Sara R., Turner, Anne-Marie W., James, Lindsey I., Tsai, Yi-Hsuan, Coffey, Alisha R., Margolis, David M., Parker, Joel, Browne, Edward P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946360/
https://ncbi.nlm.nih.gov/pubmed/33635929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009346
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