Epigenomic characterization of latent HIV infection identifies latency regulating transcription factors

Transcriptional silencing of HIV in CD4 T cells generates a reservoir of latently infected cells that can reseed infection after interruption of therapy. As such, these cells represent the principal barrier to curing HIV infection, but little is known about their characteristics. To further our unde...

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Bibliografiska uppgifter
I publikationen:PLoS Pathog
Huvudupphovsmän: Jefferys, Stuart R., Burgos, Samuel D., Peterson, Jackson J., Selitsky, Sara R., Turner, Anne-Marie W., James, Lindsey I., Tsai, Yi-Hsuan, Coffey, Alisha R., Margolis, David M., Parker, Joel, Browne, Edward P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2021
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946360/
https://ncbi.nlm.nih.gov/pubmed/33635929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009346
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