Ancestral haplotype reconstruction in endogamous populations using identity-by-descent

In this work we develop a novel algorithm for reconstructing the genomes of ancestral individuals, given genotype or sequence data from contemporary individuals and an extended pedigree of family relationships. A pedigree with complete genomes for every individual enables the study of allele frequen...

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Bibliographic Details
Published in:PLoS Comput Biol
Main Authors: Finke, Kelly, Kourakos, Michael, Brown, Gabriela, Dang, Huyen Trang, Tan, Shi Jie Samuel, Simons, Yuval B., Ramdas, Shweta, Schäffer, Alejandro A., Kember, Rachel L., Bućan, Maja, Mathieson, Sara
Format: Artigo
Language:Inglês
Published: Public Library of Science 2021
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946327/
https://ncbi.nlm.nih.gov/pubmed/33635861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008638
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