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Approximating Identity-by-Descent Matrices Using Multiple Haplotype Configurations on Pedigrees
Identity-by-descent (IBD) matrix calculation is an important step in quantitative trait loci (QTL) analysis using variance component models. To calculate IBD matrices efficiently for large pedigrees with large numbers of loci, an approximation method based on the reconstruction of haplotype configur...
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| Format: | Artigo |
| Jezik: | Inglês |
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Copyright © 2005 by the Genetics Society of America
2005
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1456528/ https://ncbi.nlm.nih.gov/pubmed/15965257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.040337 |
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