Approximating Identity-by-Descent Matrices Using Multiple Haplotype Configurations on Pedigrees

Identity-by-descent (IBD) matrix calculation is an important step in quantitative trait loci (QTL) analysis using variance component models. To calculate IBD matrices efficiently for large pedigrees with large numbers of loci, an approximation method based on the reconstruction of haplotype configur...

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Bibliographic Details
Main Authors: Gao, Guimin, Hoeschele, Ina
Format: Artigo
Language:Inglês
Published: Copyright © 2005 by the Genetics Society of America 2005
Subjects:
Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456528/
https://ncbi.nlm.nih.gov/pubmed/15965257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.040337
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