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Approximating Identity-by-Descent Matrices Using Multiple Haplotype Configurations on Pedigrees

Identity-by-descent (IBD) matrix calculation is an important step in quantitative trait loci (QTL) analysis using variance component models. To calculate IBD matrices efficiently for large pedigrees with large numbers of loci, an approximation method based on the reconstruction of haplotype configur...

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Main Authors: Gao, Guimin, Hoeschele, Ina
Formato: Artigo
Idioma:Inglês
Publicado: Copyright © 2005 by the Genetics Society of America 2005
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456528/
https://ncbi.nlm.nih.gov/pubmed/15965257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.040337
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