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Effect of severe renal impairment on pharmacokinetics, safety, and tolerability of lemborexant
The primary aim of this study was to examine the effect of severe renal impairment (SRI) on the pharmacokinetics of lemborexant, a dual orexin receptor antagonist indicated for the treatment of insomnia. A phase 1 multicenter, single‐dose, open‐label, parallel‐group study was conducted in subjects w...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Pharmacol Res Perspect |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
John Wiley and Sons Inc.
2021
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7945683/ https://ncbi.nlm.nih.gov/pubmed/33689224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.734 |
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