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Effect of severe renal impairment on pharmacokinetics, safety, and tolerability of lemborexant

The primary aim of this study was to examine the effect of severe renal impairment (SRI) on the pharmacokinetics of lemborexant, a dual orexin receptor antagonist indicated for the treatment of insomnia. A phase 1 multicenter, single‐dose, open‐label, parallel‐group study was conducted in subjects w...

詳細記述

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書誌詳細
出版年:Pharmacol Res Perspect
主要な著者: Landry, Ishani, Aluri, Jagadeesh, Hall, Nancy, Filippov, Gleb, Dayal, Satish, Moline, Margaret, Reyderman, Larisa
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7945683/
https://ncbi.nlm.nih.gov/pubmed/33689224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.734
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