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Effect of severe renal impairment on pharmacokinetics, safety, and tolerability of lemborexant
The primary aim of this study was to examine the effect of severe renal impairment (SRI) on the pharmacokinetics of lemborexant, a dual orexin receptor antagonist indicated for the treatment of insomnia. A phase 1 multicenter, single‐dose, open‐label, parallel‐group study was conducted in subjects w...
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| 出版年: | Pharmacol Res Perspect |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2021
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7945683/ https://ncbi.nlm.nih.gov/pubmed/33689224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.734 |
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