The long noncoding RNA MALAT1 modulates adipose loss in cancer-associated cachexia by suppressing adipogenesis through PPAR-γ

BACKGROUND: Cancer-associated cachexia is a multifactorial syndrome defined by progressive weight loss with ongoing loss of adipose tissue and skeletal muscle. Adipose loss occurs in the early stage of cachexia and is associated with reduced quality of life and survival time. Although numerous lncRN...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nutr Metab (Lond)
Main Authors: Han, Jun, Shen, Lei, Zhan, Zheng, Liu, Yuguo, Zhang, Chang, Guo, Ruochen, Luo, Yangjun, Xie, Zhiqin, Feng, Ying, Wu, Guohao
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2021
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7944636/
https://ncbi.nlm.nih.gov/pubmed/33691715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12986-021-00557-0
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