The long noncoding RNA MALAT1 modulates adipose loss in cancer-associated cachexia by suppressing adipogenesis through PPAR-γ

BACKGROUND: Cancer-associated cachexia is a multifactorial syndrome defined by progressive weight loss with ongoing loss of adipose tissue and skeletal muscle. Adipose loss occurs in the early stage of cachexia and is associated with reduced quality of life and survival time. Although numerous lncRN...

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發表在:Nutr Metab (Lond)
Main Authors: Han, Jun, Shen, Lei, Zhan, Zheng, Liu, Yuguo, Zhang, Chang, Guo, Ruochen, Luo, Yangjun, Xie, Zhiqin, Feng, Ying, Wu, Guohao
格式: Artigo
語言:Inglês
出版: BioMed Central 2021
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7944636/
https://ncbi.nlm.nih.gov/pubmed/33691715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12986-021-00557-0
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