The long noncoding RNA MALAT1 modulates adipose loss in cancer-associated cachexia by suppressing adipogenesis through PPAR-γ

BACKGROUND: Cancer-associated cachexia is a multifactorial syndrome defined by progressive weight loss with ongoing loss of adipose tissue and skeletal muscle. Adipose loss occurs in the early stage of cachexia and is associated with reduced quality of life and survival time. Although numerous lncRN...

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Detalhes bibliográficos
Publicado no:Nutr Metab (Lond)
Main Authors: Han, Jun, Shen, Lei, Zhan, Zheng, Liu, Yuguo, Zhang, Chang, Guo, Ruochen, Luo, Yangjun, Xie, Zhiqin, Feng, Ying, Wu, Guohao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7944636/
https://ncbi.nlm.nih.gov/pubmed/33691715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12986-021-00557-0
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