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Viral Subpopulation Screening Guides in Designing a High Interferon-Inducing Live Attenuated Influenza Vaccine by Targeting Rare Mutations in NS1 and PB2 Proteins

Influenza A viruses continue to circulate among wild birds and poultry worldwide, posing constant pandemic threats to humans. Effective control of emerging influenza viruses requires new broadly protective vaccines. Live attenuated influenza vaccines with truncations in nonstructural protein 1 (NS1)...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Ghorbani, Amir, Abundo, Michael C., Ji, Hana, Taylor, Kara J. M., Ngunjiri, John M., Lee, Chang-Won
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7944443/
https://ncbi.nlm.nih.gov/pubmed/33115873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01722-20
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