Computationally Optimized Broadly Reactive H2 HA Influenza Vaccines Elicited Broadly Cross-Reactive Antibodies and Protected Mice from Viral Challenges

Influenza viruses have caused numerous pandemics throughout human history. The 1957 influenza pandemic was initiated by an H2N2 influenza virus. This H2N2 influenza virus was the result of a reassortment event between a circulating H2N2 avian virus and the seasonal H1N1 viruses in humans. Previously...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Reneer, Z. Beau, Jamieson, Parker J., Skarlupka, Amanda L., Huang, Ying, Ross, Ted M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2020
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7944441/
https://ncbi.nlm.nih.gov/pubmed/33115871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01526-20
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