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Rationale and Application of PEGylated Lipid-Based System for Advanced Target Delivery of siRNA

RNA interference (RNAi) technology has become a powerful tool in application of unraveling the mechanism of disease and may hold the potential to be developed for clinical uses. Small interfering RNA (siRNA) can bind to target mRNA with high specificity and efficacy and thus inhibit the expression o...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Ge, Xuemei, Chen, Lijuan, Zhao, Bo, Yuan, Weien
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7944141/
https://ncbi.nlm.nih.gov/pubmed/33716725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.598175
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