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Recent advances in siRNA delivery mediated by lipid-based nanoparticles

Small interfering RNA (siRNA) has been expected to be a unique pharmaceutic for the treatment of broad-spectrum intractable diseases. However, its unfavorable properties such as easy degradation in the blood and negative-charge density are still a formidable barrier for clinical use. For disruption...

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Podrobná bibliografie
Vydáno v:Adv Drug Deliv Rev
Hlavní autoři: Yonezawa, Sei, Koide, Hiroyuki, Asai, Tomohiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier B.V. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406478/
https://ncbi.nlm.nih.gov/pubmed/32768564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2020.07.022
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