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Rationale and Application of PEGylated Lipid-Based System for Advanced Target Delivery of siRNA

RNA interference (RNAi) technology has become a powerful tool in application of unraveling the mechanism of disease and may hold the potential to be developed for clinical uses. Small interfering RNA (siRNA) can bind to target mRNA with high specificity and efficacy and thus inhibit the expression o...

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Détails bibliographiques
Publié dans:Front Pharmacol
Auteurs principaux: Ge, Xuemei, Chen, Lijuan, Zhao, Bo, Yuan, Weien
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7944141/
https://ncbi.nlm.nih.gov/pubmed/33716725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.598175
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