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AKT-dependent signaling of extracellular cues through telomeres impact on tumorigenesis
The telomere-bound shelterin complex is essential for chromosome-end protection and genomic stability. Little is known on the regulation of shelterin components by extracellular signals including developmental and environmental cues. Here, we show that human TRF1 is subjected to AKT-dependent regula...
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| Publicado no: | PLoS Genet |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7942993/ https://ncbi.nlm.nih.gov/pubmed/33690611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009410 |
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