BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling

OBJECTIVE: Colorectal cancer remains the fourth most common cause of cancer-related mortality worldwide. Here we investigate the role of nuclear factor-κB (NF-κB) co-factor B-cell CLL/lymphoma 3 (BCL-3) in promoting colorectal tumour cell survival. DESIGN: Immunohistochemistry was carried out on 47...

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Vydáno v:Gut
Hlavní autoři: Urban, Bettina C, Collard, Tracey J, Eagle, Catherine J, Southern, Samantha L, Greenhough, Alexander, Hamdollah-Zadeh, Maryam, Ghosh, Anil, Poulsom, Richard, Paraskeva, Christos, Silver, Andrew, Williams, Ann C
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2016
Témata:
Colon
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941180/
https://ncbi.nlm.nih.gov/pubmed/26033966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-308270
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