Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2

Drug repurposing is a rapid approach to identify therapeutics for the treatment of emerging infectious diseases such as COVID-19. To address the urgent need for treatment options, we carried out a quantitative high-throughput screen using a SARS-CoV-2 cytopathic assay with a compound collection of 8...

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Publicado en:Front Pharmacol
Main Authors: Chen, Catherine Z., Shinn, Paul, Itkin, Zina, Eastman, Richard T., Bostwick, Robert, Rasmussen, Lynn, Huang, Ruili, Shen, Min, Hu, Xin, Wilson, Kelli M., Brooks, Brianna M., Guo, Hui, Zhao, Tongan, Klump-Thomas, Carleen, Simeonov, Anton, Michael, Samuel G., Lo, Donald C., Hall, Matthew D., Zheng, Wei
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7942396/
https://ncbi.nlm.nih.gov/pubmed/33708112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.592737
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