Persistent SARS-CoV-2 infection and increasing viral variants in children and young adults with impaired humoral immunity

BACKGROUND: There is increasing concern that persistent infection of SARS-CoV-2 within immunocompromised hosts could serve as a reservoir for mutation accumulation and subsequent emergence of novel strains with the potential to evade immune responses. METHODS: We describe three patients with acute l...

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Publicado no:medRxiv
Main Authors: Truong, Thao T., Ryutov, Alex, Pandey, Utsav, Yee, Rebecca, Goldberg, Lior, Bhojwani, Deepa, Aguayo-Hiraldo, Paibel, Pinsky, Benjamin A., Pekosz, Andrew, Shen, Lishuang, Boyd, Scott D., Wirz, Oliver F., Röltgen, Katharina, Bootwalla, Moiz, Maglinte, Dennis T., Ostrow, Dejerianne, Ruble, David, Han, Jennifer H., Biegel, Jaclyn A., Li, Maggie, Huang, ChunHong, Sahoo, Mayala K., Pannaraj, Pia S., O’Gorman, Maurice, Judkins, Alexander R., Gai, Xiaowu, Bard, Jennifer Dien
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7941650/
https://ncbi.nlm.nih.gov/pubmed/33688673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.02.27.21252099
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