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Increased viral variants in children and young adults with impaired humoral immunity and persistent SARS-CoV-2 infection: A consecutive case series

BACKGROUND: There is increasing concern that persistent infection of SARS-CoV-2 within immunocompromised hosts could serve as a reservoir for mutation accumulation and subsequent emergence of novel strains with the potential to evade immune responses. METHODS: We describe three patients with acute l...

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Publicado no:EBioMedicine
Main Authors: Truong, Thao T., Ryutov, Alex, Pandey, Utsav, Yee, Rebecca, Goldberg, Lior, Bhojwani, Deepa, Aguayo-Hiraldo, Paibel, Pinsky, Benjamin A., Pekosz, Andrew, Shen, Lishuang, Boyd, Scott D., Wirz, Oliver F., Röltgen, Katharina, Bootwalla, Moiz, Maglinte, Dennis T., Ostrow, Dejerianne, Ruble, David, Han, Jennifer H., Biegel, Jaclyn A., Li, Maggie, Huang, ChunHong, Sahoo, Malaya K., Pannaraj, Pia S., O'Gorman, Maurice, Judkins, Alexander R., Gai, Xiaowu, Dien Bard, Jennifer
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072072/
https://ncbi.nlm.nih.gov/pubmed/33915337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2021.103355
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