Resolving the Dynamic Motions of SARS-CoV-2 nsp7 and nsp8 Proteins Using Structural Proteomics

Coronavirus (CoV) non-structural proteins (nsps) assemble to form the replication-transcription complex (RTC) responsible for viral RNA synthesis. nsp7 and nsp8 are important cofactors of the RTC, as they interact and regulate the activity of RNA-dependent RNA polymerase (RdRp) and other nsps. To da...

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Publicat a:bioRxiv
Autors principals: Courouble, Valentine V., Dey, Sanjay Kumar, Yadav, Ruchi, Timm, Jennifer, Harrison, Jerry Joe E. K., Ruiz, Francesc X., Arnold, Eddy, Griffin, Patrick R.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7941636/
https://ncbi.nlm.nih.gov/pubmed/33688660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.03.06.434214
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