A hepatitis B virus transgenic mouse model with a conditional, recombinant, episomal genome

BACKGROUND & AIMS: Development of new and more effective therapies against hepatitis B virus (HBV) is limited by the lack of suitable small animal models. The HBV transgenic mouse model containing an integrated overlength 1.3-mer construct has yielded crucial insights, but this model unfortunate...

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Vydáno v:JHEP Rep
Hlavní autoři: Kruse, Robert L., Barzi, Mercedes, Legras, Xavier, Pankowicz, Francis P., Furey, Nika, Liao, Lan, Xu, Janming, Bissig-Choisat, Beatrice, Slagle, Betty L., Bissig, Karl-Dimiter
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940981/
https://ncbi.nlm.nih.gov/pubmed/33733079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhepr.2021.100252
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