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Stigmasterol Simultaneously Induces Apoptosis and Protective Autophagy by Inhibiting Akt/mTOR Pathway in Gastric Cancer Cells

BACKGROUND: Stigmasterol (SS) has been proven to possess potential anticancer activities in several cancer cell lines, but its molecular mechanism is still unknown. Thus, we investigated whether SS has the capabilities of inducing autophagy and its molecular mechanisms in gastric cancer cells. METHO...

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Foilsithe in:Front Oncol
Main Authors: Zhao, Huange, Zhang, Xian, Wang, Min, Lin, Yingying, Zhou, Songlin
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940753/
https://ncbi.nlm.nih.gov/pubmed/33708631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.629008
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