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Stigmasterol Simultaneously Induces Apoptosis and Protective Autophagy by Inhibiting Akt/mTOR Pathway in Gastric Cancer Cells

BACKGROUND: Stigmasterol (SS) has been proven to possess potential anticancer activities in several cancer cell lines, but its molecular mechanism is still unknown. Thus, we investigated whether SS has the capabilities of inducing autophagy and its molecular mechanisms in gastric cancer cells. METHO...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Zhao, Huange, Zhang, Xian, Wang, Min, Lin, Yingying, Zhou, Songlin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940753/
https://ncbi.nlm.nih.gov/pubmed/33708631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.629008
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