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Homotaurine limits the spreading of T cell autoreactivity within the CNS and ameliorates disease in a model of multiple sclerosis

Most multiple sclerosis (MS) patients given currently available disease-modifying drugs (DMDs) experience progressive disability. Accordingly, there is a need for new treatments that can limit the generation of new waves T cell autoreactivity that drive disease progression. Notably, immune cells exp...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tian, Jide, Song, Min, Kaufman, Daniel L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940650/
https://ncbi.nlm.nih.gov/pubmed/33686135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-84751-3
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