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Identification of chemical compounds regulating PD-L1 by introducing HiBiT-tagged cells

Programmed death-ligand 1 (PD-L1) is a co-inhibitory molecule expressed on tumor cells. Immune checkpoint inhibitors focusing on the PD-L1 mechanism are now being studied for the treatment of various cancer types. However, the regulatory mechanism of PD-L1 is yet to be fully clarified, and a high-th...

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Podrobná bibliografie
Vydáno v:FEBS Lett
Hlavní autoři: Uchida, Yutaro, Matsushima, Takahide, Kurimoto, Ryota, Chiba, Tomoki, Inutani, Yuki, Asahara, Hiroshi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940577/
https://ncbi.nlm.nih.gov/pubmed/33421110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.14032
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