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Using the novel HiBiT tag to label cell surface relaxin receptors for BRET proximity analysis

Relaxin family peptide 1 (RXFP1) is the receptor for relaxin a peptide hormone with important therapeutic potential. Like many G protein‐coupled receptors (GPCRs), RXFP1 has been reported to form homodimers. Given the complex activation mechanism of RXFP1 by relaxin, we wondered whether homodimeriza...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Hoare, Bradley L., Kocan, Martina, Bruell, Shoni, Scott, Daniel J., Bathgate, Ross A. D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6667744/
https://ncbi.nlm.nih.gov/pubmed/31384473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.513
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