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Oxidation inhibits autophagy protein deconjugation from phagosomes to sustain MHC class II restricted antigen presentation

LC3-associated phagocytosis (LAP) contributes to a wide range of cellular processes and notably to immunity. The stabilization of phagosomes by the macroautophagy machinery in human macrophages can maintain antigen presentation on MHC class II molecules. However, the molecular mechanisms involved in...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ligeon, Laure-Anne, Pena-Francesch, Maria, Vanoaica, Liliana Danusia, Núñez, Nicolás Gonzalo, Talwar, Deepti, Dick, Tobias P., Münz, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940406/
https://ncbi.nlm.nih.gov/pubmed/33686057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21829-6
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